====== Diversity and Dynamics of Genomes (Seminar) ======
\\ 


|392217 | Wittler | Winter 2014 |Tuesday 14-16 in U10-146|[[http://ekvv.uni-bielefeld.de/kvv_publ/publ/vd?id=44147758|ekvv]] |

===== Course Description =====
In this seminar, research of the DiDy Group is presented, and other research related topics are discussed. This semester, the faculty will introduce themselves / their research. 



===== Schedule =====

|  **Date** | **Who/What**  |
|  7.10. | Administratives, Update on our research |
| 14.10. | Roland: How I became a Scientific Coordinator and some science that is left behind. Journal screening? Blogs? |
| 21.10. | Wiki hands-on (update research page) |
| 28.10. | Alexander Sczyrba |
|  4.11. | Barbara Hammer |
| 11.11. | Benedikt B., Georges, Yoga, Dany, Nina, Benedikt L., ... Who are you again? I don't care about your science!  |
| 18.11. | Markus, Liren, Lu, Tina, Nicole, Linda, ... |
| 25.11. | Ellen Baake |
|  2.12. | Stefan Albaum |
|  9.12. | [[:MichaelBarton|Guest: Michael Barton, JGI]] |
| 16.12. | Xmas market |
|  6.1.  | --- |
| 13.1.  | --- |
| 20.1.  |  |
| 27.1.  | Robert Giegerich: "Mind over matter, matter over mind? Encouraging news about Pareto optimization in dynamic programming" (Abstract below) |
|  3.2.  | Update on our research |
| ??     | Tim Nattkemper |

=== Robert Giegerich: "Mind over matter, matter over mind? Encouraging news about Pareto optimization in dynamic programming" ===
Combinatorial optimization minimizes a "cost" function. When true costs are involved -- in terms of money, energy, computation time -- it is not a problem to optimize under multiple objectives. True costs simply add up. But what if our objectives are incommensurable: 


  * Sequence similarity versus folding energy?\\ Preservation of specific motifs versus overall conservation?\\ Maximizing similarity versus minimizing partner switching? 
Should we choose love over gold, gold over love, or what else? 

Pareto optimization avoids the artificial combination of diverse objectives. It gives the best of two worlds in a mathematically strict sense, is safe to use, and has efficient implementations.