====== Bioinformatics Journal Club (2S) ======

| 392172 | Feijao, Dörr | Winter 2016/17 | Monday 16:00-17:30 in U10-155 | [[https://ekvv.uni-bielefeld.de/kvv_publ/publ/vd?id=79062529|ekvv]] |

===== Contents =====

In this seminar we read and discuss current research articles from different fields in bioinformatics. Each participant must present in few minutes two articles of their choice one week before their presentation. The group then votes which article will be discussed in detail in the subsequent week. To this end, the participant who proposed the article will take the lead of the discussion. All participants must read the paper and prepare themselves for the discussion. 

The topics of presented papers should be related to bioinformatics, biology, or computer science. 

This year we have a different format for choosing the papers, called the "Secret Santa Journal Club".
Everybody picks a paper that s/he always wanted/had to read but never did. Them, writes the reference on a piece of paper. We put all papers in a bag and everybody pulls one, and this paper will then be presented by the non-expert who pulled it from the bag. The drawing will be on 24.10.2016.

===== Schedule =====

| **Date** | **Chapter(s)** | **Name** | **Remarks** |
| 17.10.2016 | Organization of the journal club | Pedro Feijao | |
| 24.10.2016 | Wichteln | everybody |
| 31.10.2016 | --- | (Brückentag) |
| 07.11.2016 | Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomes {{http://dx.doi.org/10.1186/1471-2164-15-S6-S4|[PDF]}}  | Olga  |
| 14.11.2016 | Tests for gene clustering  {{http://dx.doi.org/10.1089/10665270360688129|[PDF]}} | Pedro |
| 21.11.2016 |Evolutionary history of human disease genes reveals phenotypic connections and comorbidity among genetic diseases. {{http://dx.doi.org/10.1038/srep00757|[PDF]}}  | Omar |
| 28.11.2016 | --- postponed --- | |
| 05.12.2016 | MetaboAnalyst: A web server for metabolomic data analysis and interpretation {{http://dx.doi.org/10.1093/nar/gkp356|[PDF]}} | Fabian |
| 12.12.2016 | Assessing the robustness of parsimonious predictions for gene neighborhoods from reconciled phylogenies {{http://dx.doi.org/10.1007/978-3-319-19048-8_22|[PDF]}} | Kostas |
| 19.12.2016 | --- postponed --- | |
| 26.12.2016 | --- | |
| 02.01.2017 | --- | |
| 09.01.2017 | A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity {{http://dx.doi.org/10.1126/science.1225829|[PDF]}}| Jens |
| 16.01.2017 | HySA: A Hybrid Structural variant Assembly approach using next generation and single-molecule sequencing technologies {{http://dx.doi.org/10.1101/069815|[PDF]}}| Roland |
| 23.01.2017 | Edit Distance Cannot Be Computed in Strongly Subquadratic Time (unless SETH is false). {{http://dx.doi.org/10.1145/2746539.2746612|[PDF]}} | Dany | Lipton's {{http://rjlipton.wordpress.com/2015/06/01/puzzling-evidence|blog}} |
| 30.01.2017 | Best-of Posts on Scientific Blogs | everybody |
| 06.02.2017 | Science on Twitter | Jens & Dany|


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