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--- teaching:2009winter:algogefo [2010/02/04 10:24]
+++ teaching:2009winter:algogefo [2020/02/14 09:07] (current)
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+====== Algorithmen in der Genomforschung ======
+\\
+|392109/392110 |Marília Braga, Jens Stoye |Winter 2009/2010 |Fr 10:15-11:45/Fr 8:45-10:15 |[[http://ekvv.uni-bielefeld.de/kvv_publ/publ/vd?id=12921437|ekvv]]/[[http://ekvv.uni-bielefeld.de/kvv_publ/publ/vd?id=12921491|ekvv]] |
+==== Contents: ====
+Die funktionelle Analyse molekularer Genomdaten ist eine der großen Herausforderungen an die Bioinformatik. In dieser Veranstaltung werden die Grundlagen für bioinformatische Techniken in der Genomforschung behandelt. Hierunter fallen Algorithmen zur Genomkartierung und -assemblierung, Methoden zur funktionellen Genomannotation, insbesondere Genvorhersage und -funktionsbestimmung, Verfahren zur Analyse von DNA-Microarrays und Massenspektren, Methoden und Modelle zur Proteinstrukturvorhersage sowie Algorithmen zum Vergleich zweier oder mehrerer Genome.
+==== Literature: ====
+D. W. Mount. Bioinformatics: Sequence and Genome Analysis. Cold Spring Harbor Laboratory Press, 2001.
+The page [[teaching:alggrliterature|AlgGRLiterature]] contains many links to the original literature.
+==== Time table: ====
+| **Date** | **Topic** | **Exercises** |
+| 16.10.2009 | Introduction, logistics | (none) |
+| 23.10.2009 | 23 SNP-disease associations | {{ 449exercises01associationMapping.pdf | Number 1 }} |
+| 30.10.2009 | 20 Genome rearrangement I (M. Braga) | {{ 449exercises02reversals.pdf | Number 2 }} |
+| 06.11.2009 | 20 Genome rearrangement II (M. Braga) | {{ 449exercises03reversalsB.pdf | Number 3 }} |
+| 13.11.2009 | 20 Genome rearrangement III (M. Braga) | {{ 449exercises04reversalsC.pdf | Number 4 }} |
+| 20.11.2009 | 20 Genome rearrangement IV (M. Braga) | {{ 449exercises05dcj.pdf | Number 5 }} |
+| 27.11.2009 | 04 Genome assembly I: traditional assembly | {{ 449exercises06assembly.pdf | Number 6 }} |
+| 04.12.2009 | 05 Genome assembly II: HTS assembly | {{ 449exercises07htsAssembly.pdf | Number 7 }} |
+| 11.12.2009 | 12 Transcriptomics I: mRNA analysis | {{ 449exercises08mRNAs.pdf | Number 8 }} |
+| 18.12.2009 | 12.5 Transcriptomics II: microarray design | {{ 449exercises09microarrayDesign.pdf | Number 9 }} |
+| 08.01.2010 | 13 Transcriptomics III: microarray analysis | {{ 449exercises10microarrayAnalysis.pdf | Number 10 }} |
+| 15.01.2010 | 15 Computational Proteomics I: comparison of 2D gels | {{ 449exercises11twoDgels.pdf | Number 11 }} |
+| 22.01.2010 | 16 Computational Proteomics II: mass spectrometry (peptide sequencing, PMF) | {{ 449exercises12massSpec.pdf | Number 12 }} |
+| 29.01.2010 | 24 Computational Metagenomics I | {{ 449exercises13metagenomics.pdf | Number 13 }} |
+| 05.02.2010 | Q&As | |(numbers refer to chapters in [[teaching:alggrliterature|AlgGRLiterature]])
+==== Organisational Matters: ====
+Together with the practical course "Bioinformatische Anwendungen in der Genomforschung" in the following summer semester, this lecture forms the master module [[http://www.zfl.uni-bielefeld.de/studium/module/techfak/modulhandbuch/#algorithmen_genomforschung|Algorithms in Genome Research]].\\ The exercises will not be corrected or graded, but presence and activity during the exercise hours is expected. Credit points will be given based on an oral exam at the end of the semester.
+Back to [[:teaching|Teaching]]

Genome Informatics

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