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research [2017/01/23 12:37]
Pina Krell [High Throughput Sequencing]
research [2017/01/23 14:53] (current)
Pina Krell [High Throughput Sequencing]
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 === High-throughput analysis of T-cell and B-cell receptor repertoire data === === High-throughput analysis of T-cell and B-cell receptor repertoire data ===
 +{{:​research:​immunosubs.jpg?​400 |}}
 Highly variable cell surface receptors of B cells and T cells are, as part of the human immune system, responsible for fending of everyday molecular threats to human life, for example pathogenous infective agents. Highly variable cell surface receptors of B cells and T cells are, as part of the human immune system, responsible for fending of everyday molecular threats to human life, for example pathogenous infective agents.
 Single nucleotide variation in the sequence of individual receptor molecules create a variable pool, the receptor repertoire, able to encounter the vast molecular variability of microbial pathogenic attack. Loss of variation in the receptor pool is thought to result in increasing susceptibility to severe infections possibly leading to death. ​ Single nucleotide variation in the sequence of individual receptor molecules create a variable pool, the receptor repertoire, able to encounter the vast molecular variability of microbial pathogenic attack. Loss of variation in the receptor pool is thought to result in increasing susceptibility to severe infections possibly leading to death. ​
research.txt · Last modified: 2017/01/23 14:53 by Pina Krell