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Practical Course: Bioinformatics Applications in Genome Research


392181 Schulz Block 09.03.2020-20.03.2020 - 9:30-17:30 Uhr in V6-116 ekvv

Content

In this course, practical applications and issues in concrete problem statements and handling real data sets will be addressed. The following topics are intended: assembly, scaffolding, annotation, gene prediction, comparative analysis, etc.

Theoretical knowledge of the students shall be supplemented by practical aspects such as setting up and running existing tools, implementing small own tools, pre- and postprocessing, and critical interpretation of results. A continuously enriched visualization of the data and the obtained results will also guide through the course.

  • Requires participation in the lecture “Algorithms in Genome Research” or similar.
  • Beside regular and active participation in the course, each student gives a short (15min) presentation and presents their results to the other participants.

Overview

Date Topic Presentation Solution (for next day)
Mon, 9.3. Shell Tizian: Introduction to Python
Tue, 10.3. Assembly TBA: Genome Assembly, de Brujin Graphs
Wed, 11.3. Finishing TBA: BWA
Thu, 12.3. Genome rearrangements I TBA: Rearrangement distances
Fri, 13.3. Genome rearrangements II TBA: Circos tutorial
Mon, 16.3. Gene Prediction TBA: Gene Prediction (software: Glimmer, Prodigal)
Tue, 17.3. Hidden Markov Models (HMMs) TBA: HMMs
Wed, 18.3. Position-Specific Scoring Matrices (PSSMs) TBA: PSSMs
Thu, 19.3. Metagenomics TBA: Metagenomics
Fri, 20.3. Finishing the Circos plot

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