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--- thesistopics [2021/05/25 12:24] – rwittler
+++ thesistopics [2026/07/19 16:41] (current) – jstoye
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 </WRAP>
+===== <TITLE> (Bachelor/Master) =====
-===== Improvement of Sequence-to-Graph Alignment (Bachelor) =====
+<Project description>
-[[https://ekvv.uni-bielefeld.de/pers_publ/publ/PersonDetail.jsp?personId=70863414|Tizian Schulz]] //(Please also refer to the project page: [[https://gitlab.ub.uni-bielefeld.de/gi/plast|PLAST]])//
-PLAST is a new heuristic method to find maximum scoring local alignments of a DNA query sequence to a pangenome represented as a compacted colored de Bruijn graph. The first method has been published [[https://doi.org/10.1093/bioinformatics/btab077|here]], but there exist various ideas how to improve the method. Some are well suited for a Bachelor thesis. Contact Tizian for details.
-===== Medical Bioinformatics Projects in Australia (Master) =====
-[[https://ekvv.uni-bielefeld.de/pers_publ/publ/PersonDetail.jsp?personId=65864|Jens Stoye]], [[https://genomics.uq.edu.au/profile/263/lutz-krause|Lutz Krause]] //(University of Queensland Diamantina Institute, Brisbane, Australia)//
-In collaboration with the Computational Clinical Genomics Group at the University of Queensland Diamantina Institute, Brisbane, Australia, we develop and apply bioinformatics and data-mining methods in the context of biomedical research. Student projects are available in the context of biomarker discovery for cancer, genome-wide epigenetic association studies, analysis of next-generation sequencing data, mining and visualizing the human microbiota, evolutionary genomics of human parasites, calling structural variants from next-generation sequencing data and genome-wide association studies (GWAS).

Genome Informatics

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