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Practical Course: Bioinformatics Applications in Genome Research

392181 Bohnenkämper Block 18.03.- 28.03. 9:30-17:30

Content

In this course, practical applications and issues in concrete problem statements and handling real data sets will be addressed. The following topics are intended: assembly, scaffolding, annotation, gene prediction, comparative analysis, etc.

Theoretical knowledge of the students shall be supplemented by practical aspects such as setting up and running existing tools, implementing small own tools, pre- and postprocessing, and critical interpretation of results. A continuously enriched visualization of the data and the obtained results will also guide through the course.

  • Requires participation in the lecture “Algorithms in Genome Research” or similar.
  • Beside regular and active participation in the course, each student gives a short (15min) presentation and presents their results to the other participants.

Overview

Putative Schedule below; may be subject to change.

Date Topic Presentation Solution (for next day)
Mon, 18.03. Shell/Snakemake Crash Course
Tue, 19.03. Assembly
Wed, 20.03. Finishing
Thu, 21.03. Gene Prediction
Fri, 22.03. Genome rearrangements
Mon, 25.03. Hidden Markov Models (HMMs)
Tue, 26.03. Position-Specific Scoring Matrices (PSSMs)
Wed, 27.03. Haplotype Inference
Thu, 18.03. Metagenomics

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