Algorithms in Genome Research

392109/10 Stoye, Robidou Winter 2024/25 Fr 9:00-10:30 and 10:30-12:00 in U10-146

Contents

This class covers the basic algorithmic techniques used in the computational analysis of genome and post-genome data. This includes algorithms for genomic mapping and assembly, methods for functional genome annotation (gene finding and gene function prediction), algorithms for the analysis of DNA microarrays and mass spectra, methods and models for protein structure prediction, and algorithms for comparative genomics.

Literature

The page AlgGRLiterature contains many links to the original literature.

Time table

Date Topic Exercises
11.10.2024 Introduction, logistics
18.10.2024 Physical mapping (JS) Exercises 1
25.10.2024 Sequence analysis (LR)
01.11.2024 (holiday)
08.11.2024 Comparative genomics I (JS) Exercises 3
15.11.2024 Comparative genomics II (JS) Exercises 4
22.11.2024 Genome assembly I (LR)
29.11.2024 Genome assembly II (LR)
06.12.2024 Genome assembly III (LR)
13.12.2024 Transcriptomics (JS) Exercises 8
20.12.2024 Proteomics (mass spectrometry) (JS) Exercises 9
Winter break
10.01.2025 Haplotype inference (JS) Exercises 10
17.01.2025 SNP-disease association mapping (JS) Exercises 11
24.01.2025 Pangenomics (LR) Exercises 12
31.01.2025 Metagenomics (LR)

Examination dates

Oral exams will be on 17 February 2025 or later. Please make an appointment with our team assistants Nicole Schellenberg or Verena Uhlig.

A second oral exam can be taken in March 2025. Please contact one of the team assistants if you are interested.